Test Code HODGE Carbapenemase Detection, Modified Hodge Test
Reporting NameCarbapenamase-Modified Hodge Test
Determining carbapenem resistance
Modified Hodge Test
Performing LaboratoryMayo Medical Laboratories in Rochester
Specimen Volume: Isolate
1. Submit Enterobacteriaceae species in pure culture, actively growing.
2. Place specimen in a large infectious container (Supply T146) and label as an etiologic agent/infectious substance.
1. Specimen source and organism identification are required.
2. See Infectious Specimen Shipping Guidelines in Special Instructions for shipping information.
Forms: If not ordering electronically, submit a Microbiology Request Form (Supply T244) with the specimen.
Specimen Stability Information
Day(s) and Time(s) Performed
Monday through Sunday
Test ClassificationThis test uses a standard method. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.
CPT Code Information
LOINC Code Information
|Result ID||Reporting Name||LOINC Code|
|HODGE||Carbapenamase-Modified Hodge Test||In Process|
Resistance to antibiotic therapy via production of the enzyme carbapenemase by Klebsiella pneumoniae and other members of Enterobacteriaceae is becoming more common. This resistance is not always detected by conventional antimicrobial susceptibility testing, which may result in inappropriate antimicrobial therapy for the patient.
In Enterobacteriaceae, the gene blaKPC, which encodes KPC (Klebsiella pneumoniae carbapenemase) production, can be detected by real-time PCR. However, molecular methods have not been established for other carbapenemases.
The modified Hodge test, a phenotypic method, is recommended by the Clinical and Laboratory Standards Institute (CLSI) as the method to detect carbapenemases.
A positive result indicates the production of carbapenemase.
A negative result indicates the lack of production of carbapenemase.
Analytic Time2 days
Reject Due To
|Test ID||Reporting Name||Available Separately||Always Performed|
|HODGB||Carbapenamase-Modified Hodge Test||No, (Bill Only)||Yes|