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HelpTest Code CCMVU Congenital Cytomegalovirus (cCMV), Molecular Detection, PCR, Urine
Ordering Guidance
This test should be ordered to test urine specimens from patients aged 21 days or younger. To test urine from patients older than 21 days, order CMVPV / Cytomegalovirus (CMV) Molecular Detection, PCR, Varies.
To test saliva specimens from patients aged 21 days or younger, order CCMVS / Congenital Cytomegalovirus (cCMV), Molecular Detection, PCR, Saliva. To test saliva from patients older than 21 days, order CMVPV / Cytomegalovirus (CMV) Molecular Detection, PCR, Varies.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Container/Tube: Plastic sterile container, 5 mL
Specimen Volume: 0.2 mL
Collection Instruction:
1. Collect a random urine from a urine bag, container, or catheter.
2. Transfer urine to sterile container.
3. No preservative
Useful For
Aiding in the rapid diagnosis of cytomegalovirus infections in neonates 21 days of age or younger using urine specimens
Method Name
Real-Time Polymerase Chain Reaction (PCR)
Reporting Name
Congenital CMV, PCR, UrineSpecimen Type
UrineSpecimen Minimum Volume
0.1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Frozen | 72 hours |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Clinical Information
Cytomegalovirus (CMV) is a double-stranded DNA virus of the Herpesviridae family. CMV is transmitted through direct contact from a variety of infected body fluids, as well as through sexual contact, organ transplantation, and intrauterine transmission during pregnancy.(1) CMV infection may be asymptomatic but can cause a wide range of symptoms, especially in immunocompromised individuals. Congenitally acquired CMV (cCMV) may lead to long-term sequelae, including visual and hearing impairments, and cognitive and motor deficits.(2) Current recommendations indicate testing urine and saliva swabs for cCMV using a nucleic acid amplification detection method.(3)
Reference Values
Negative
Interpretation
A positive result indicates the presence of cytomegalovirus (CMV) DNA in the patient sample.
A negative result indicates the absence of CMV DNA in the patient sample.
An invalid result indicates inability to conclusively determine presence or absence of CMV DNA in the patient sample.
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 to 2 daysSpecimen Retention Time
3 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
87496
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CCMVU | Congenital CMV, PCR, Urine | 4999-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 620658 | Congenital CMV, PCR, Urine | 4999-9 |