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HelpTest Code FRFIT Rabies Antibody Endpoint
Specimen Required
Specimen Type: Serum
Container/Tube: Red
Specimen Volume: 2 mL
Collection Instructions: Draw blood in a plain red-top tube(s), Spin down and send 2 mL of serum refrigerated in a plastic vial.
Note: 1. Serum gel tube is acceptable, but must be poured off into plastic vial.
2. Collection date is required.
Method Name
Serum Neutralization Fluorescent Antibody
Reporting Name
Rabies RFFIT Endpoint, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 60 days |
Reject Due To
| Hemolysis | Mild OK; Gross reject |
| Lipemia | Mild OK; Gross reject |
| Icterus | NA |
| Other | NA |
Reference Values
Reportable range is 0.1 to 15.0 IU/mL
Less than 0.1 IU/mL: Below detection limit
In humans a results of 0.5 IU/mL or higher is considered an acceptable response to rabies vaccination according to the World Health Organization (WHO) guidelines; see WHO and Advisory Committee on Immunization Practices documents for additional guidance.
Interpretation
Quantitative results. For those who want to know their exact titer between the reportable range.
RFFIT stands for Rapid Fluorescent Foci Inhibition Test. It is a serum neutralization (inhibition) test, which means it measures the ability of rabies specific antibodies to neutralize rabies virus and prevent the virus from infecting cells. The antibodies are called rabies virus neutralizing antibodies (RVNA).
Day(s) Performed
Monday, Wednesday, Thursday
Report Available
21 to 35 daysPerforming Laboratory
RFFIT/K-State Rabies Laboratory Manhattan/K-State Innovation CenterCPT Code Information
86382
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FRFIT | Rabies RFFIT Endpoint, S | 6524-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z2071 | Rabies Titer-Response | 6524-3 |